【2008】
- Tamba, S., Yodoi, R., Segi-Nishida, E., Ichikawa, A., Narumiya, S., and Sugimoto, Y. Timely interaction between prostaglandin and chemokine signaling is a prerequisite for successful fertilization. (2008) Proc. Natl. Acad. Sci. USA,105, 14539-14544.
- Yano, Y., Yano, A., Oishi, S., Fujii, N., Sugimoto, Y., and Matsuzaki, K. Coiled-coil tag-robe system for quick labeling of membrane receptors in living cells.(2008) ACS Chem. Biol., 3, 341-345.
- Yano, Y., Shimbo, T., Sugimoto, Y., and Matsuzaki, K. Intracellular third loop-C-terminal tail interaction in prostaglandin EP3β receptor. (2008) Biochem. Biophys. Res. Commun., 371, 846-849.
- Takano, H., Nakazawa, S., Okuno, Y., Shirata, N., Tsuchiya, S., Kainoh, T., Takamatsu, S., Furuta, K., Taketomi, Y., Naito, Y., Takematsu, H., Kozutsumi, Y., Tsujimoto, G., Murakami, M., Kudo, I., Ichikawa, A., Nakayama, K., Sugimoto, Y., and Tanaka, A. Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells. (2008) FEBS Lett. 582, 1444-1450.
- Tsuchiya, H., Oka, T., Nakamura, K., Ichikawa, A., Saper, C. B., and Sugimoto, Y. Prostaglandin E2 attenuates preoptic expression of GABAA receptors via EP3 receptors. (2008)J. Biol. Chem. 283, 11064-11071.
- Yuhki, K.I., Ushikubi, F., Naraba, H., Ueno, A., Kato, H., Kojima, F., Narumiya, S., Sugimoto, Y., Matsushita, M., and Oh-Ishi, S. Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy.(2008) J. Pharmacol. Exp. Ther.325, 601-609.
- Esumi, S., Wu, S-X., Yanagawa, Y., Obata, K., Sugimoto, Y., and Tamamaki, N. Method for single-cell microarray analysis and application to gene-expression profiling of GABAergic neuron progenitors.(2008) Neurosci. Res. 60, 439-451.
- Yellon, S. M., Ebner, C. A., and Sugimoto, Y. Parturition and recruitment of macrophages in cervix of mice lacking the prostaglandin F receptor.(2008) Biol. Reprod. 78, 438-444.
- Kawamata, M., Yoshida, M. Sugimoto, Y., Kimura, T., Tonomura, Y., Takayanagi, Y., Yanagisawa, T., and Nishimori, K. Infusion of oxytocin induces successful delivery in prostanoid FP-receptor-deficient mice. (2008) Mol. Cell. Endocrinol. 283, 32-37.
【2007】
- Hoshino, T., Nakaya, T., Homan, T., Tanaka, K., Sugimoto, Y., Araki, W., Narita, M., Narumiya, S., Suzuki, T., and Mizushima, T. Involvement of prostaglandin E2 in production of amyloid-peptides both in vitro and in vivo.(2007) J. Biol. Chem. 282, 32676-32688.
- Suzuki-Yamamoto, T., Sugimoto, Y, Ichikawa, A., and Ishimura, K.Co-localization of prostaglandin F synthase, cyclooxygenase-1 and prostaglandin F receptor in mouse Leydig cells. (2007) Histochem. Cell Biol. 128(4),317-322.
- Taketomi, Y., Sunaga, K,. Tanaka, S., Nakamura, M., Arata, S., Okuda, T., Moon, T.C., Chang, H.W., Sugimoto, Y., Kokame, K., Miyata, T., Murakami, M., and Kudo, I.Impaired mast cell maturation and degranulation and attenuated allergic responses in ndrg1-deficient mice. (2007) J. Immunol. 178, 7042-7053.
- Furuta, K., Nakayama, K., Sugimoto, Y., Ichikawa, A., and Tanaka, S.Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815. (2007) J. Biol. Chem. 282 (18), 13438-13446.
- Sugimoto, Y., and Narumiya, S.Prostaglandin E receptors. (2007) J. Biol. Chem. 282 (16), 11613-11617.
- Kawamata, M., Tonomura, Y., Kimura, T., Sugimoto, Y., Yanagisawa, T., and Nishimori, K.Oxytocin-induced phasic and tonic contractions are modulated by the contractile machinery rather than the quantity of oxytocin receptor. (2007) Am. J. Physiol. Endocrinol. Metab. 292 (4), E992-E999.
【2006】
- Yokoyama, U., Minamisawa, S., Hong, Q., Ghatak, S., Akaike, T., Segi-Nishida, E., Iwasaki, S., Iwamoto, M., Misra, S., Tamura, K., Hori, H., Yokota, S., Toole, B.P., Sugimoto, Y., and Ishikawa, Y.Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. (2006) J. Clin. Invest. 116, 3026-3034.
- Osada, S., Naganawa, A., Misonou, M., Tsuchiya. S., Tamba, S., Okuno, Y., Nishikawa, J., Satoh, K., Imagawa, I, Tsujimoto, G., Sugimoto, Y., and Nishihara, T.Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenesis. (2006) Toxicol. Lett. 167, 106-113.
- Trivedi, D.B., Sugimoto, Y., and Loftin, C.D.Attenuated cyclooxygenase-2 expression contributes to patent ductus arteriosus in preterm mice. (2006) Pediatr. Res. 60, 669-674.
- Shioji, M., Fukuda, H., Kanzaki, T., Wasada, K., Kanagawa, T., Shimoya, K., Mu, J., Sugimoto, Y., Murata, Y.Reduction of aquaporin-8 on fetal membranes under oligohydramnios in mice lacking prostaglandin F2 alpha receptor. (2006) J. Obstet. Gynaecol. Res. 32, 373-378.
- Kim, H., Arakawa, H., Hatae, N., Sugimoto, Y., Matsumoto, O., Osada, T., Ichikawa, A., Ikai, A. Quantification of the number of EP3 receptors on a living CHO cell surface by the AFM.(2006)Ultramicroscopy. 106, 652-662.
【2005】
- Liu, Y.,
Furuta, K., Teshima, R., Shirata, N., Sugimoto, Y., Ichikawa, A. and Tanaka,
S.Critical
role of PKC[beta]II in activation of mast cells by monomeric IgE. (2005) J. Biol. Chem., 280, 38976-38981.
- Shoji, Y., Takahashi, M., Takasuka, N., Niho, N., Kitamura, T., Sato, H.,
Maruyama, T., Sugimoto, Y., Narumiya, S., Sugimura, T. and Wakabayashi, K.Prostaglandin
E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis.(2005)
Carcinogenesis, 12, 2116-2122.
- Sugimoto, Y., Fukada, Y., Mori,
D., Tanaka, S., Yamane, H., Okuno, Y., Deai, K., Tsuchiya, S., Tsujimoto,
G. and Ichikawa, A.Prostaglandin
E2 stimulates granulocyte colony-stimulating factor production via the prostanoid
EP2 receptor in mouse peritoneal neutrophils. (2005) J. Immunol., 175, 2606-2612.
- Takasaki, I., Nojima, H., Shiraki, K., Sugimoto,
Y., Ichikawa, A., Ushikubi, F., Narumiya, S. and Kuraishi, Y.Involvement
of cyclooxygenase-2 and EP(3) prostaglandin receptor in acute herpetic but
not postherpetic pain in mice. (2005)
Neuropharmacol.,49, 283-292.
- Kunikata,
T., Yamane, H., Segi, E., Matsuoka, T., Sugimoto, Y., Tanaka, S., Tanaka,
H., Nagai, H., Ichikawa, A. and Narumiya, S.Suppression
of allergic inflammation by the prostaglandin E receptor subtype EP3. (2005) Nat. Immunol.,
6, 524-531.
- Moriyama, T., Higashi, T., Togashi, K., Iida, T., Segi, E., Sugimoto, Y.,
Tominaga, T., Narumiya, S. and Tominaga, M.Sensitization
of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins.
(2005) Mol. Pain,
1, 1-13.
- Foyouzi, N., Cai, Z.,
Sugimoto, Y. and Stocco, C.Changes in the expression of steroidogenic and antioxidant
genes in the mouse corpus luteum during luteolysis. (2005) Biol. Reprod., 72,1134-1141.
- Tanaka, S., Mikura, S., Hashimoto, E., Sugimoto, Y. and
Ichikawa, A.Ca2+
influx-mediated histamine synthesis and IL-6 release in mast cells activated
by monomeric IgE. (2005) Eur. J. Immunol., 35, 460-468.
- Hirasawa, A., Tsumaya, K., Awaji, T., Katsuma, S.,
Adachi, T., Yamada, M., Sugimoto, Y., Miyazaki, S. and Tsujimoto, G.Free fatty acids regulate gut incretin glucagon-like peptide-1
secretion through GPR120. (2005)
Nature Med., 11, 90-94.
【2004】
- Tsuboi, H., Sugimoto, Y., Kainoh, T. and Ichikawa, A.Prostanoid
EP4 receptor is involved in suppression of 3T3-L1 adipocyte differentiation. (2004) Biochem.
Biophys. Res. Commun., 322, 1066-1072.
- Sugimoto, Y., Tsuboi, H., Okuno, Y., Tamba, S.,
Tsuchiya, S., Tsujimoto, G. and Ichikawa, A.Microarray
evaluation of EP4 receptor-mediated prostaglandin E2 suppression of 3T3-L1
adipocyte differentiation. (2004) Biochem. Biophys.
Res. Commun., 322, 911-917.
- Shoji,
Y., Takahashi, M., Kitamura, T., Watanabe, K., Kawamori, T., Maruyama, T.,
Sugimoto, Y., Negishi, M., Narumiya, S., Sugimura, T. and Wakabayashi, K.Downregulation
of prostaglandin E receptor subtype EP3 during colon cancer development.
(2004) Gut., 53, 1151-1158.
- Tanaka, S., Deai, K., Konomi, A., Takahashi, K., Yamane, H., Sugimoto,
Y. and Ichikawa, A.Expression
of L-histidine decarboxylase in granules of elicited mouse polymorphonuclear
leukocytes. (2004) Eur. J. Immunol., 34, 1472-1482.
- Sugimoto, Y., Nakato, T., Kita, A.,
Takahashi, Y., Hatae, N., Tabata, H., Tanaka, S. and Ichikawa, A.A
cluster of aromatic amino acids in the i2 loop plays a key role for Gs coupling
in prostaglandin EP2 and EP3 receptors. (2004) J.
Biol. Chem., 279, 11016-11026.
【2003】
- Oka, T., Oka, K., Kobayashi, T., Sugimoto, Y., Ichikawa,
A., Ushikubi, F., Narumiya, S. and Saper, CB.Characteristics
of thermoregulatory and febrile responses in mice deficient in prostaglandin
EP1 and EP3 receptors. (2003) J. Physiol.,551,
945-954.
- Sugimoto, Y., Nakato, T., Kita, A., Hatae, N., Tabata, H., Tanaka, S. and
Ichikawa, A.Functional
domains essential for Gs activity in prostaglandin EP2 and EP3 receptors.
(2003) Life Sci., 74, 135-141.
- Tsuchiya, S., Tanaka, S.,
Sugimoto, Y., Katsuyama, M., Ikegami, R. and Ichikawa, A.Identification
and characterization of a novel progesterone receptor-binding element in the
mouse prostaglandin E receptor subtype EP2 gene. (2003) Genes
to Cells, 8, 747-758.
- Saito, O., Guan, Y., Qi,
Z., Davis, LS., Komhoff, M., Sugimoto, Y., Narumiya, S., Breyer, RM. and Breyer,
MD.Expression
of the prostaglandin F receptor (FP) gene along the mouse
genitourinary tract. (2003) Am. J. Physiol. Renal
Physiol., 284, F1164-1170.
- Minami, T., Matsumura, S., Mabuchi, T., Kobayashi, T.,
Sugimoto, Y., Ushikubi, F., Ichikawa, A., Narumiya, S. and Ito, S.Functional
evidence for interaction between prostaglandin EP3 and kappa-opioid receptor
pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1)
glycoprotein gp120. (2003)
Neuropharmacol., 45, 96-105.
- Shoda, J., Ueda, T., Kawamoto, T., Todoroki,
T., Asano, T., Sugimoto, Y., Ichikawa, A., Maruyama, T., Nimura, Y. and Tanaka,
N.Prostaglandin
E receptors in bile ducts of hepatolithiasis patients and the pathobiological
significance for cholangitis. (2003) Clin. Gastroenterol. Hepatol., 1, 285-296.
- Tsuboi, K., Iwane, A., Nakazawa, S., Sugimoto, Y. and Ichikawa, A.Role
of prostaglandin H2 synthase 2 in murine parturition: study on ovariectomy-induced
parturition in prostaglandin F receptor-deficient
mice. (2003)
Biol. Reprod., 69, 195-201.
- Hatae, N., Kita, A., Tanaka,
S., Sugimoto, Y. and Ichikawa, A.Induction
of adherent activity in mastocytoma P-815 cells by the cooperation of two
prostaglandin E2 receptor subtypes, EP3 and EP4.(2003) J. Biol. Chem.,
278, 17977-17981.
- Mu, J., Kanzaki, T., Si, X., Tomimatsu, T., Fukuda,
H., Shioji, M., Murata, Y., Sugimoto, Y. and Ichikawa, A.Apoptosis
and related proteins in placenta of intrauterine fetal death in prostaglandin
F receptor-deficient mice. (2003) Biol.
Reprod., 68, 1968-1974.
- Segi, E., Haraguchi, K., Sugimoto, Y., Tsuji, M., Tsunekawa, H., Tamba, S.,
Tsuboi, K., Tanaka, S. and Ichikawa, A.Expression
of messenger RNA for prostaglandin E receptor subtypes EP4/EP2 and cyclooxygenase
isozymes in mouse periovulatory follicles and oviducts during superovulation. (2003) Biol. Reprod.,
68, 804-811.
- Amano, H., Hayashi, I., Endo, H., Kitasato, H., Yamashina, S.,
Maruyama, T., Kobayashi, M., Satoh, K., Narita, M., Sugimoto, Y., Murata,
T., Yoshimura, H., Narumiya, S. and Majima, M.Host
prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and
tumor growth. (2003) J. Exp. Med.,
197, 221-232.
【2002】
- Tsuboi, K., Sugimoto, Y. and Ichikawa, A.Prostaglandin E2 and F2 alpha
in mouse reproduction. (2002) International
Congress Series, 3rd International Conference on Oxygen and Life (Ishimura,
Y., ed.), 1233, 397-404.
- Tsuboi, K., Sugimoto, Y. and Ichikawa, A.Prostanoid
receptor subtypes. (2002) Prostaglandins
& other Lipid Mediators, 68-69, 535-556.
- Tsuboi, K., Segi, E., Sugimoto,
Y. and Ichikawa, A.Role of prostanoids on female
reproduction revealed by receptor-deficient mice. (2002) Recent Res. Devel. Endocrinol.,
3, 119-126.
- Tabata, H., Tanaka, S., Sugimoto, Y., Kanki, H., Kaneko,
S. and Ichikawa, A.Possible
coupling of prostaglandin E receptor EP1 to TRP5 expressed in Xenopus
laevis oocytes. (2002) Biochem. Biophys. Res. Commun.,
298, 398-402.
- Asano,
T., Shoda, J., Ueda, T., Kawamoto, T., Todoroki, T., Shimonishi, M., Tanabe,
T., Sugimoto, Y., Ichikawa, A., Mutoh, M., Tanaka, N. and Miwa, M.Expressions
of cyclooxygenase-2 and prostaglandin E-receptors in carcinoma of the gallbladder:
crucial role of arachidonate metabolism in tumor growth and progression. (2002)
Clin. Cancer Res., 8, 1157-1167.
- Mu,J.,Kanzaki,t.,Tomimatsu,T.,Fukuda,H.,Wasada,K.,Fujii,E.,Endoh,M.,Kozuki,M.,Murata,Y.,Sugimoto,Y.,and Ichikawa,A.Expression
of apoptosis in placentae from mice lacking the prostaglandin F receptor.(2002) Placenta,
23, 215-223.
- Hatae, N., Sugimoto,
Y. and Ichikawa, A.Prostaglandin
receptors: Advances in the study of EP3 receptors signaling. (2002) J. Biochem., 131, 781-784.
- Safina,F.,Tanaka,S.,Inagaki,M.,Tuboi,K.,Sugimoto,Y.,and Ichilawa,A.,Expression
of L-histidine decarboxylase in mouse male germ cells. (2002) J.
Biol. Chem., 277, 14211-14215.
- Kabashima,K.,Murata,T.,Nagamachi,M.,Matsuoka,T.,Segi,E.,Tsuboi,K.,Sugimoto,Y.,Kobayashi,T.,Miyachi,Y.,Ichikawa,A.,and Narumiya,S.The
prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell
activation in the gut.(2002) J. Clin. Invest.,
109, 883-893.
- Yoshida,K.,Oida,H.,Kobayashi,T.,Maruyama,T.,Tanaka,M.,Katayama,T.,Yamaguchi,K.,Segi,E.,Tsuboyama,T.,Matsushita,M.,Ito,K.,Ito,Y.,Sugimoto,Y.,Ushikubi,F.,Ohuchida,S.,Kondo,K.,Nakamura,T.and Narumiya,S.Stimulation
of bone formation and prevention of bone loss by prostaglandin E EP4 receptor
activation. (2002) Proc. Natl. Acad. Sci. USA, 99,
4580-4585.
- Mu,J.,Kanzaki,T.,Si,X.,Tomimatsu,T.,Fukuda,H.,Fujii,E.,Hosono,T.,Murata,Y.,Sugimoto,Y.and Ichikawa,A.Apoptosis
and related proteins during parturition in prostaglandin F receptor-deficient
mice. (2002) Biochem. Biophys.
Res. Commun., 292, 675-681.
- Fennekohl,A.,Sugimoto,Y.,Segi,E.,Maruyama,T.,Ichikawa,A.and Puschel,G.P.Contribution
of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor to the
inhibition by PGE2 of the LPS-induced TNF alpha -formation in Kupffer cells
from EP2-or EP4-receptor-deficient mice. Pivotal role for the EP4-receptor
in wild type Kupffer cells. (2002) J. Hepatol., 36,
328-334.
- Mutoh,M.,Watanabe,K.,Kitamura,T.,Shoji,Y.,Takahashi,M.,Kawamori,T.,Tani,K.,Kobayashi,M.,Maruyama,T.,Kobayashi,K.,Ohuchida,S.,Sugimoto,Y.,Narumiya,S.,Sugimura,T.and Wakabayashi,K.Involvement
of prostaglandin E receptor subtype EP(4) in colon carcinogenesis. (2002) Cancer Res.,
62, 28-32.
- Torii,E.,Segi,E.,Sugimoto,Y.,Takahashi,K.,Kabashima,K.,Ikai,K.and Ichikawa,A.Expression
of prostaglandin E2 receptor subtypes in mouse hair follicles. (2002) Biochem. Biophys. Res. Commun., 290, 696-700.
- Hatae,N.,Yamaoka,K.,Sugimoto,Y.,Negishi,M.and Ichikawa,A. Augmentation
of receptor-mediated adenylyl cyclase activity by Gi-coupled prostaglandin
receptor subtype EP3 in a G beta gamma subunit-independent manner. (2002) Biochem.
Biophys. Res. Commun., 290, 1, 162-168.
【2001】
- Ma, H., Hara, A., Xiao,
C-Y., Okada, Y., Takahata, O., Nakaya, K., Sugimoto, Y., Ichikawa, A., Narumiya,
S. and Ushikubi, F. Increased
bleeding tendency and decreased susceptibility to thromboembolism in mice
lacking the prostaglandin E receptor subtype EP3. (2001) Circulation, 104, 1176-1180.
- Sonoshita, M., Takaku, K., Sasaki, N., Sugimoto, Y., Ushikubi,
F., Narumiya, S., Oshima, M. and Taketo, MM. Acceleration
of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716)
knockout mice. (2001) Nat. Med.,
7, 1048-1051.
- Ueno, A., Matsumoto, H., Naraba, H., Ikeda, Y., Ushikubi,
F., Matsuoka, T., Narumiya, S., Sugimoto, Y., Ichikawa, A. and Oh-ishi, S. Major
roles of prostanoid receptors IP and EP3 in endotoxin-induced enhancement
of pain perception.
(2001) Biochem. Pharmacol., 62, 157-160.
- Minami, T., Nakano, H., Kobayashi,
T., Sugimoto, Y., Ushikubi, F., Ichikawa, A., Narumiya, S. and Ito, S. Characterization
of EP receptor subtypes responsible for prostaglandin E2-induced pain responses
by use of EP1 and EP3 receptor knockout mice. (2001)
Br. J. Pharmacol., 133, 438-444.
- Shinomiya, S., Naraba, H., Ueno, A., Utsunomiya, I., Maruyama,
T., Ohuchida, S., Ushikubi, F., Yuki, K., Narumiya, S., Sugimoto, Y., Ichikawa,
A. and Oh-ishi, S. Regulation
of TNF alpha and interleukin-10 production by prostaglandins I2 and E2: studies
with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective
synthetic agonists. (2001) Biochem. Pharmacol., 61, 1153-1160.
- The
expression of prostaglandin E receptors EP2 and EP4 and their different regulation
by LPS in C3H/HeN peritoneal macrophages. Ikegami, R., Sugimoto, Y., Segi,
E., Katsuyama, M., Karahashi, H., Amano, F., Maruyama, T., Yamane, H., Tsuchiya,
S. and Ichikawa, A. (2001) J. Immunol., 166, 4689-4696.
【2000】
- Sakuma, Y., Tanaka, K., Suda, M., Komatsu, Y., Yasoda,
A., Miura, M., Ozasa, A., Narumiya, S., Sugimoto, Y., Ichikawa, A., Ushikubi,
F. and Nakao, K. Impaired
bone resorption by lipopolysaccharide in vivo in mice deficient in the prostaglandin
E receptor EP4 subtype. (2000) Infect. Immun., 68(12), 6819-6825.
- Yamane, H.,
Sugimoto, Y., Tanaka, S. and Ichikawa, A. Prostaglandin
E2 receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production
induced by lipopolysaccharide in mouse peritoneal neutrophils. (2000) Biochem. Biophys.
Res. Commun., 278, 224-228.
- Matsuoka, T., Hirata, M., Tanaka, H.,
Takahashi, Y., Murata, T., Kabashima, K., Sugimoto, Y., Kobayashi, T., Ushikubi,
F., Aze, Y., Eguchi, N., Urade, Y., Yoshida, N., Kimura, K., Mizoguchi, A.,
Honda, Y., Nagai, H. and Narumiya, S. Prostaglandin
D2 as a mediator of allergic asthma. (2000) Science, 287,
2013-2017.
- Stocco, CO., Zhong, L., Sugimoto, Y., Ichikawa,
A., Lau, LF. and Gibori, G. Prostaglandin
F2 alpha-induced expression of 20 alpha-hydroxysteroid dehydrogenase involves
the transcription factor NUR77.(2000) J. Biol. Chem., 275(47),
37202-37211.
- Ushikubi, F., Sugimoto, Y., Ichikawa, A. and Narumiya, S. Roles
of prostanoids revealed from studies using mice lacking specific prostanoid
receptors. (2000)
Jpn. J. Pharmacol., 83, 279-285.
- Miyaura, C., Inada, M., Suzawa, T., Sugimoto, Y., Ushikubi, F., Ichikawa,
A., Narumiya, S. and Suda, T .Impaired
bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout
mice. (2000) J. Biol. Chem., 275,
19819-19823
- Sugimoto,
Y., Narumiya, S. and Ichikawa, A. Distribution
and function of prostanoid receptors: studies from knockout mice. (2000) Prog. Lipid Res.,
39, 289-314.
- Suzawa,
T., Miyaura, C., Inada, M., Maruyama, T., Sugimoto, Y., Ushikubi, F., Ichikawa,
A., Narumiya, S. and Suda, T. The
role of prostaglandin E receptor subtypes (EP1, EP2, EP3 and EP4) in bone
resorption: An analysis using specific agonists for the respective EPs. (2000) Endocrinology, 141(4),
1554-1559.
- Croy, B.A., Chantakru,
S., Narumiya, S., Ichikawa, A. and Sugimoto, Y. Prolonged
gestation does not extend survival of uterine Natural Killer lymphocytes in
mice deleted in the receptor for prostaglandin F2 alpha. (2000) J. Reprod.
Immunol., 46, 125-129.
- Sakuma, Y., Tanaka, K.,
Suda, M., Yasoda, A., Natsui, K., Tanaka, I., Ushikubi, F., Narumiya, S.,
Segi, E., Sugimoto, Y., Ichikawa, A. and Nakao, K. Crucial
involvement of the EP4 subtype of prostaglandin E receptor in osteoclast formation
by proinflammatory cytokines and lipopolysaccharide. (2000) J. Bone
Miner. Res., 15, 218-227.
- Tsuboi, K., Sugimoto, Y., Iwane,
A., Yamamoto, K., Yamamoto, S. and Ichikawa, A. Uterine
expression of prostaglalndin H2 synthase in late pregnancy and during parturition
in prostaglandin F receptor-deficient mice. (2000) Endocrinology,
141(1), 315-324.
【1999】
- Puschel, G.P., Segi, E., Fennekohl,
A., Sugimoto, Y., Ikegami, R., Katsuyama, M. and Ichikawa, A. Role of the EP2 and EP4 receptor
in the prostaglandin E2-mediated feedback inhibition of lipopolysaccharide-induced
TNF-alpha formation in mouse kupffer cells. (1999) Cells
of the hepatic Sinusoid, 7, 260-262.
- Ishibashi, R., Tanaka, I., Kotani, M., Muro, S., Goto, M., Sugawara, A., Mukoyama,
M., Sugimoto, Y., Ichikawa, A., Narumiya, S. and Nakao, K. Roles
of prostaglandin E receptors in mesangial cells under high-glucose conditions.
(1999)
Kidney International, 56, 589-600.
- Takeuchi, K., Ukawa, H., Furukawa, O., Kawauchi,
S., Araki, H., Sugimoto, Y., Ichikawa, A., Ushikubi, F. and Narumiya, S. Prostaglandin
E receptor subtypes involved in stimulation of gastroduodenal bicarbonate
secretion in rats and mice. (1999)
J. Physiol. Pharmacol., 50 (2),155-167.
- Takeuchi, K., Ukawa, H., Kato, S., Furukawa, O.,
Araki, H., Sugimoto, Y., Ichikawa, A., Ushikubi, F. and Narumiya, S. Impaired
duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin
E-receptor subtype EP(3). (1999)
Gastroenterology, 117 (5), 1128-1135.
- Narumiya, S., Sugimoto,
Y. and Ushikubi, F. Prostanoid
receptors: structures, properties, and functions. (1999) Physiol. Rev., 79 (4), 1193-1226.
- Wang, J., Yamamoto, K., Sugimoto, Y., Ichikawa, A. and Yamamoto,
S. Induction
of prostaglandin I2 receptor by tumor necrosis factor alpha in osteoblastic
MC3T3-E1 cells. (1999) Biochim. Biophys. Acta, 1441, 69-76.
- Hosokawa,
H., Ninomiya, H., Sawamura, T., Sugimoto, Y., Ichikawa, A., Fujiwara, K. and
Masaki, T. Neuron-specific
expression of cationic amino acid transporter 3 in the adult rat brain. (1999) Brain Res., 838, 158-165.
- Hizaki, H., Segi, E., Sugimoto, Y., Hirose, M., Ushikubi,
F., Matsuoka, T., Noda, Y., Tanaka, T., Yoshida, N., Narumiya, S. and Ichikawa,
A. Abortive
expansion of the cumulus and impaired fertility in mice lacking the prostaglandin
E receptor subtype EP2. (1999) Proc. Natl. Acad. Sci. USA, 96, 10501-10506.
【1998】
- Sugimoto, Y., Segi, E., Tsuboi, K.,
Ichikawa, A. and Narumiya, S. Female
reproduction in mice lacking the prostaglandin F receptor; roles of prostaglandin
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of the LPS-stimulated expression of EP2 and EP4 prostaglandin E receptors
in mouse macrophage-like cell line, J774.1. (1998) Biochem. Biophys.
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T., Hizaki, H., Tsuboi, K., Katsuyama, M., Ichikawa, A., Tanaka, T., Yoshida,
N. and Narumiya, S. Impaired
febrile response in mice lacking the prostaglandin E receptor subtype EP3.
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T., Murata, T., Matsuoka, T., Ushikubi, F., Hirose, M., Tanaka, T., Yoshida,
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ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient
mice. (1998) Biochem. Biophys. Res. Commn.,
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of the gene for the mouse prostaglandin E receptor subtype EP2: tissue-specific
initiation of transcription in the macrophage and the uterus. (1998) Biochem. J., 330, 1115-1121.
【1997】
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A., Yamaguchi, M., Honda, H., Hirai, H., Negishi, M., Kakizuka, A. and Ichikawa,
A. Characterization
of the mouse prostaglandin F receptor gene: a transgenic mouse study of a
regulatory region that controls its expression in the stomach and kidney but
not in the ovary. (1997) Genes to Cells, 2, 571-580.
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F., Kobayashi, T., Hirata, M., Sugimoto, Y. and Narumiya, S. Ligand
binding specificities of the eight types and subtypes of the mouse prostanoid
receptors expressed in Chinese hamster ovary cells. (1997) Br.
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H., Mizuno, N., Ichikawa, A. and Narumiya, S. Expression
of messenger RNA for the prostaglandin D receptor in the leptomeninges of
the mouse brain. (1997) FEBS Lett.,
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pain perception and inflammatory response in mice lacking prostacyclin receptor. (1997) Nature, 388, 6643, 678-682.
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Yamasaki, A., Segi, E., Tsuboi, K., Aze, Y., Nishimura, T., Oida, H., Yoshida,
N., Tanaka, T., Katsuyama, M., Hasumoto, K., Murata, T., Hirata, M., Ushikubi,
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of parturition in mice lacking the prostaglandin F receptor. (1997) Science,
277, 681-683.
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Kinoshita, Y., Kishi, K., Nakata, H., Hassan, S., Kawanami, C., Sugimoto,
Y., Katsuyama, M., Negishi, M., Narumiya, S., Ichikawa, A. and Chiba, T. Distribution
of prostaglandin E receptors in the rat gastrointestinal tract. (1997)
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K., Kinoshita, Y., Negishi, M., Chiba, T., Narumiya, S. and Ichikawa A. Cellular
localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal
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of expression of mRNA encoding the PGF2 alpha receptor with luteal cell apoptosis
in ovaries of pseudopregnant mice. (1997) J.
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S.K., Wang, J., Sugimoto, Y, Ichikawa, A. and Dey, S.K. Potential
sites of prostaglandin actions in the periimplantation mouse uterus: differential
expression and regulation of prostaglandin receptor genes. (1997) Biol.
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cellular localization of the messenger ribonucleic acid for prostaglandin
E receptor subtypes in the mouse uterus during pseudopregnancy. (1997) Endocrinology, 138 (1), 344-350.
【1996】
- Ichikawa, A., Sugimoto, Y. and Negishi, M. Molecular
aspects of the structures and functions of the prostaglandin E receptors.
(1996) J. Lipid Mediat.
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Todo, N., Sugimoto, Y., Ichikawa, A. and Narumiya, S. Membrane
depolarization by activation of prostaglandin E receptor EP3 subtype of putative
serotonergic neurons in the dorsal raphe nucleus of the rat. (1996) Naunyn-Schmiedeberg's
Arch. Pharmacol., 353, 377-381.
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Y., Ichikawa, A., Narumiya, S., Taketo, M.M. and Seldin, M. F. Mapping
of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors.
(1996)
Genomics, 32, 285-288.
【1995】
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Ichikawa, A. and Narumiya, S. In
situ hybridization studies of prostacyclin receptor mRNA expression in various
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E receptors. (1995) J.
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mechanisms of diverse actions of prostanoid receptors. (1995) Biochim. Biophys. Acta, 1259,
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mouse prostaglandin E receptor EP2 subtype: cloning, expression, and Northern
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151-156.
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Narumiya, S., Sugimoto, Y., Honda, A., Ichikawa, A., Chiba, T. and Kinoshita,
Y. Copresence
of prostaglandin EP2 and EP3 receptors on gastric enterochromaffin-like cell
carcinoid in African rodents. (1995) Gastroenterology, 109, 341-347.
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Kurozumi, S. and Ichikawa, A. Selective
coupling of prostaglandin E receptor EP3D to multiple G proteins depending
on interaction of the carboxylic acid of agonist and arginine residue of seventh
transmembrane domain. (1995) Biochem. Biophys. Res. Commun.,
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coupling of prostaglandin E receptor EP3D to Gi and Gs through interaction
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A. and Negishi, M. Characterization
of the signal transduction of prostaglandin E receptor EP1 subtype in cDNA-transfected
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S. and Ichikawa, A. Identification
of prostaglandin E receptor 'EP2' cloned from mastocytoma cells as EP4 subtype.
(1995) FEBS Lett., 364, 339-341.
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transductions of three isoforms of mouse prostaglandin E receptor EP3 subtype. (1995) Adv. PG, TX, LT Res., 23, 255-257.
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H., Sugimoto, Y., Sawada, M., Negishi, M., Suzumura, A., Marunouchi, T., Ichikawa,
A. and Baba, A. cDNA
cloning of a thromboxane A2 receptor from rat astrocytes. (1995) Biochim. Biophys. Acta, 1265, 220-223.
【1994】
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Harazono, A, Sugimoto, Y., Hazato, A., Kurozumi, S. and Ichikawa, A. TEI-3356,
a highly selective agonist for the prostaglandin EP3 receptor. (1994)
Prostaglandins, 48, 275-283.
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J., Hashimoto, H., Sugimoto, Y., Negishi, M., Aino, H., Gotoh, M., Ichikawa,
A. and Baba, A. Cloning
and expression of a cDNA for rat prostaglandin F2 alpha receptor. (1994) Prostaglandins, 48, 31-41.
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and Negishi, M.Mouse
prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA-transfected
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A. and Negishi, M. The
C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation
of GTP-binding protein. (1994) Eur. J. Biochem., 224, 161-166.
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M., Narumiya, S. and Ichikawa, A. Distribution
of the messenger RNA for the prostaglandin E receptor subtype EP3 in the mouse
nervous system. (1994) Neurosci., 62, 919-928.
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Negishi, M. Enhancement
of adenylate cyclase stimulation by prostaglandin E receptor EP3 subtype isoforms
with different efficiencies. Harazono, (1994) Biochem. Biophys. Res. Commun., 201, 340-345.
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T., Usui, T., Tanaka., I., Mori, K., Sasaki, Y., Fukuda, Y., Namba, T., Sugimoto,
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cloning and expression of rat prostaglandin E receptor EP2 subtype. (1994) Biochem. Biophys.
Res. Commun., 200, 1329-1333.
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A. and Narumiya, S. Distinct
cellular localization of mRNAs for three subtypes of prostaglandin E receptor
in kidney. (1994) Am. J. Physiol., 266, F823-F828.
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A. Cloning
and expression of a cDNA for the human prostacyclin receptor. (1994) FEBS Lett., 344, 74-78.
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Honda, A., Negishi, M., Ichikawa, A., Narumiya, S. and Seldin, M.F. Mapping
of the genes encoding mouse thromboxane A2 receptor and prostaglandin E receptor
subtypes EP2 and EP3. (1994)
Genomics, 19, 585-588.
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A., Negishi, M., Ichikawa, A. and Narumiya, S. cDNA
cloning of a mouse prostacyclin receptor; multiple signaling pathways and
expression in thymic medulla. (1994) J. Biol. Chem.,
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Hasumoto, K., Namba, T., Irie, A., Katsuyama, M., Negishi, M., Kakizuka, A.,
Narumiya, S. and Ichikawa, A. Cloning
and expression of a cDNA for mouse prostaglandin F receptor. (1994) J. Biol. Chem., 269,
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【1993】
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A. Prostanoid
receptors and their biological actions. (1993) Prog. Lipid Res., 32, 417-434.
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T., Narumiya, S. and Ichikawa, A. Opposite
coupling of prostaglandin E receptor EP3C with Gs and Go: Stimulation of Gs
and inhibition of Go. (1993) J. Biol. Chem.,
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M., Narumiya, S. and Ichikawa, A. Third
isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal
tail coupling to both stimulation and inhibition of adenylate cyclase. (1993) Eur. J. Biochem.,
217, 313-318.
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S., Narumiya, S. and Ichikawa, A. Cloning
and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.
(1993) J. Biol. Chem.,
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F., Kakizuka, A., Ito, S., Ichikawa, A. and Narumiya, S.Alternative
splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines
G-protein specificity. (1993) Nature,
365, 166-170.
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A.Characterization
of the prostaglandin E receptor expressed on a cultured mast cell line, BNu-2cl3. (1993) Biochem. Pharmacol., 46, 863-869.
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Hayashi, Y., Ushikubi, F., Sugimoto, Y., Negishi, M. and Ichikawa, A.Structure
and function of prostanoid receptors. (1993)
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M., Sugimoto, Y., Irie, A., Narumiya, S. and Ichikawa, A.Two
isoforms of prostaglandin E receptor EP3 subtype; different COOH-terminal
domains determine sensitivity to agonist-induced desensitization. (1993) J.
Biol. Chem., 268, 9517-9521.
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A., Sugimoto, Y., Namba, T., Watabe, A., Irie, A., Negishi, M., Narumiya,
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and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype. (1993) J. Biol. Chem., 268, 7759-7762.
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Y., Hayashi, Y., Namba, T., Honda, A., Watabe, A., Narumiya, S. and Ichikawa,
A.Functional
interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide
binding proteins, showing low affinity ligand binding. (1993) Biochim. Biophys. Acta, 1175, 343-350.
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Y., Negishi, M., Hayashi, Y., Namba, T., Honda, A., Watabe, A., Hirata, M.,
Narumiya, S. and Ichikawa, A.Two
isoforms of EP3 receptor with different C-terminal domains; identical ligand
binding properties and different coupling properties with Gi proteins. (1993) J. Biol. Chem., 268,
2712-2718.
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Y., Moriwaki, T., Yamamoto, J., Ohta, M., Fukui, T. and Ichikawa, A.Nucleotide
sequence of the cDNA encoding nucleoside diphosphate kinase II derived from
spinach leaves. (1993)
Biochim. Biophys. Acta, 1171, 304-306.
【1992】
- Nomura, T., Yatsunami, K., Honda, A., Sugimoto,
Y., Fukui, T., Yamamoto, J. and Ichikawa, A.The
amino acid sequence of nucleoside diphosphate kinase I from spinach leaves,
as deduced from cDNA sequence. (1992) Arch. Biochem.
Biophys., 297, 42-45.
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M., Ichikawa, A. and Narumiya, S.Mouse
thromboxane A2 receptor; cDNA cloning, expression and northern blot analysis.
(1992) Biochem. Biophys. Res. Commun.,
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Y., Namba, T., Honda, A., Hayashi, Y., Negishi, M., Ichikawa, A. and Narumiya,
S.Cloning
and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype. (1992) J. Biol. Chem., 267, 6463-6466.
【1991】
- Sugimoto, Y., Yatsunami, K., Tsujimoto, M.,
Khorana, H.G. and Ichikawa, A.The
amino acid sequence of a glutamic acid-rich protein from bovine retina as
deduced from the cDNA sequence. (1991) Proc. Natl. Acad. Sci. USA,
88, 3116-3119.
【1990】
- Yamamoto, J., Yatsunami, K., Ohmori, E., Sugimoto, Y., Fukui, T., Katayama,
T. and Ichikawa, A.cDNA-derived
amino acid sequence of L-histidine decarboxylase from mouse mastocytoma P-815
cells. (1990) FEBS Lett., 276, 214-218.